Maternal serum magnesium is low in the second and third trimesters with gestational diabetes mellitus.82 Insulin resistance might increase the placental size leading to low placental efficiency and affect fetal growth in GDM patients.80 Magnesium, by its effects on tyrosine kinase, glucose transporter 4, and lipoprotein lipase, has a significant role in glucose metabolism (Figure 4). Here, LPL is linked to gestational diabetes.