FFRCT, fractional flow reserve derived from coronary computed tomography angiography; BMI, body mass index; MI, myocardial infarction; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol; eGFR, estimated glomerular filtration rate; HbA1c, hemoglobin A1c, NT-proBNP, N-terminal prohormone of brain natriuretic peptide; AF, atrial fibrillation. The gene discussed is NPPB; the disease is atrial fibrillation.