Probably, the role or mechanism of CD10 in the pathogenesis of colorectal cancer is induced by interaction with adhesion kinase, PI3K-AKT, and other signaling pathways, promoting cell proliferation and motility, inhibiting apoptosis, up-regulating the matrix metalloproteinase (MMPs), and promoting angiogenesis and tumorigenesis (36, 37). This evidence concerns the gene MME and colorectal cancer.