The CSF EGFR mRNA level was significantly higher in the ADEM-like phenotype than the ON phenotype (p = 0.049, p < 0.05) (Figure 3A), and the CSF NfL mRNA level was significantly higher in the ADEM-like phenotype than that in the encephalitis phenotype (p = 0.010, p < 0.05), ON phenotype (p = 0.024, p < 0.05), and control non-myelinating diseases (p = 0.002, p < 0.01) (Figure 3B). The gene discussed is NEFL; the disease is encephalitis.