Interestingly, we also observed a minor population of CD8hi T cells in several mice, which most likely represents an artefactual contamination derived from borderline gated non-TB cells, although we cannot include that they are terminally differentiated activated cytolytic T cells (27).⁠Ear inflammation was impaired in CCL18-treated CCR6−/− mice, as witness in the decreased leukocyte presence in stratum corneum and spinosum and in the dermal layer (Figure 6B). The gene discussed is CCR6; the disease is tuberculosis.