Intriguingly, we found thatELAVL3, a neural-specific RNA-binding protein, was preferentially expressed during early brain development (Fig. 3B), among the top candidates for all three disorders, with opposite effects on PTGR between SCZ/BD and ASD (Fig. 3A and3C;Supplementary Fig. 1 [available online]).ELAVL3 was upregulated in ASD, and its targets were post-transcriptionally upregulated in ASD, while it was downregulated in SCZ/BD and its targets were post-transcriptionally downregulated in SCZ/BD (Fig. 3A and3C). The gene discussed is ELAVL3; the disease is Behcet disease.