Among the AlzGene groups in Fig. 6 the SNPs in the ACE (angiotensin-converting enzyme) group have been found to reduce the Amyloid Beta peptide (A\documentclass[12pt]{minimal}\usepackage{amsmath}\usepackage{wasysym}\usepackage{amsfonts}\usepackage{amssymb}\usepackage{amsbsy}\usepackage{mathrsfs}\usepackage{upgreek}\setlength{\oddsidemargin}{-69pt}\begin{document}$$\beta$$\end{document}β) which is commonly observed in the progression of AD-related cognitive decline [40]. The gene discussed is APP; the disease is Alzheimer disease.