This is further confirmed by the fact that in a case report by Colangelo et al. [29], using an intraoperative plasma FGF23 assay, a rapid reduction in the levels of this biomarker was observed within one hour from the time of tumor excision, thus suggesting also a possible role of intraoperative FGF23 assay to guide surgery in patients with TIO. This evidence concerns the gene FGF23 and neoplasm.