CD8A and neoplasm: For example, Ifngr2 (encodes the receptor for type 1 cytokine interferon-γ (IFNγ)), was enriched in cLTMR neurons (Extended Data Fig. 5c), suggesting these neurons preferentially responded to IFNγ-producing cells, such as CD8+ T cells and NK cells, which are mediators of anti-viral and anti-tumor immunity.