The clustering of PTCs involved in unilateral ureteral obstruction (UUO) has led to the identification of six PT cell types, namely, precursor PT, S1, S2, and S3 subsets; proliferating PT subset, and profibrotic PT subset, as determined by the GSE182256 scRNA-seq dataset (Data ref: Doke et al, 2022). The gene discussed is F2; the disease is Ureteral obstruction.