As shown in Fig. 1d, a high expression level of COL11A1 mRNA was associated with worse overall survival (OS) in ER+ breast cancers excluded cases died of other causes rather than tumor, as well as in patients who received hormone therapy; additionally, high COL11A1 expression showed shorter relapse-free survival (RFS) in hormone therapy-treated cases. The gene discussed is COL11A1; the disease is neoplasm.