FKBP5 and asthma: While site-specific effects of gene expression at FKBP5 with asthma are consistent with overlapping confidence intervals, a markedly stronger effect was observed in the Brazil site (Supplementary Fig 2) which is also the site with the most severe asthmatics and highest inhaled corticosteroid (ICS) use in asthma cases (97.2%, Supplementary Data 1).