We studied the expression of the mitochondrial stop protein syntaphilin (SNPH), the mitochondrial rho protein (Miro1), the kinesin-binding proteins (TRAK1 and TRAK2), the motor kinesin (Kif5 (A, B, C) isoforms), and the ICs of the cytoplasmic dynein motor (lC1,2) in neuroblastoma cells expressing APP carrying the double Swedish familial mutations KM670/671NL (APPswe) and their control cells expressing pcDNA3.1 empty vector (Control) [29] (Fig. 1). The gene discussed is TRAK1; the disease is neuroblastoma.