Flow cytometry showed the CIN-afflicted tumors had 3-fold more CD45+ immune cells (Figure 2G – i), 2.5-fold more CD45+ CD11b+ (myeloid) cells (Figure 2G – ii), and an ~6-fold increase in F4/80-positive macrophages (Figure 2G – iii) relative to DMSO controls. Here, ITGAM is linked to cervical squamous intraepithelial neoplasia.