The DLBCL shown in Fig. 5f (overwhelming number of large blast-like cells on cytology) leaves little doubt as to the final diagnosis when the full work-up had been performed including MFC and in situ hybridization for EBV RNA and FISH for MYC gene rearrangements on a cellblock, thus revealing CD20+/CD19+/kappa+/bcl2+/CD10-/bcl6+/mum1+/CD5-/cyclinD1-/EBV-/cmyc- lymphoma cells without MYC gene rearrangement (not shown). This evidence concerns the gene CD5 and lymphoma.