LRRK2 and Parkinson disease: Moreover, cognitive symptoms were consistently reported at a lower prevalence in LRRK2 G2019S carriers with PD compared to non-carriers with idiopathic PD, which aligns with cross-sectional studies using cognitive function tests.44,45 We showed that despite a longer disease duration, LRRK2 G2019S PD was associated with a similar prevalence of motor symptoms, including postural instability, suggesting a slower rate of progression.