LRRK2 and Parkinson disease: We computed a Weibull AFT model that included known prodromal risk factors of PD on a subset of participants who had non-missing data across all covariates: n = 772 LRRK2 G2019S non-manifest, 162 LRRK2 G2019S PD, 1574 non-carrier PD and 78 445 non-carrier controls.