Immunohistochemistry (IHC) and Western blot analyses of NLRP3‐overexpressing xenografts revealed elevated intratumoural levels of pyroptosis‐associated markers (Cleaved caspase‐1 and cleaved GSDMD) relative to control tumours after sustained drug administration (Figures 2J and S4E). The gene discussed is NLRP3; the disease is neoplasm.