C3 and retinoblastoma: Histologically, the LM and IF of our patient’s RB showed features of glomerular involvement with an NM pattern and granular and subepithelial staining for IgG (3+), C3 (3+), C1q (+) and LCλ (3+) in the IF, which is uncommon in renal PLD, where null or slight staining is expected [11].