Additionally, there was an increase in mean salivary and serum IL-6 levels across all grades of OSCC, from well-differentiated squamous cell carcinoma (WDSCC) to poorly differentiated squamous cell carcinoma (PDSCC), as well as across all grades of OED, from mild dysplasia to severe dysplasia (Tables 4, 5). Here, IL6 is linked to squamous cell carcinoma.