TP53 and infection: The effectiveness of the combination of 5-FU and PDT therapy is due to increased photosensitizer accumulation and p53 induction. A combination of both therapies was recommended.Efficacy of ALA-PDT in the treatment of vitiligo.A complication of ALA-PDT in the treatment of genital warts is more frequent infections among patients. Topical application of fusidic acid or mupirocin reduced the incidence of infection.