At T1, patients with SA-AKI showed significantly elevated levels of mt-ND1 (median [IQR]; with SA-AKI 1393 [483–4 004] vs without SA-AKI 637 [313–1 523], p<0.001), mt-CO3 (with SA-AKI 686 [255–2 507] vs without SA-AKI 249 [133–1 158], p<0.001) and n-Rps18 (with SA-AKI 2 235 [602–5 773] vs without SA-AKI 890 [449–3 222], p=0.006) (Figures 6A–C). This evidence concerns the gene MT-CO3 and acute kidney injury.