MT-CO3 and Sepsis: At T1, copy numbers of mt-ND1 (median [IQR]; sepsis 963 [444–2 890] vs controls 678 [242–1 313], p=0.0006) and n-Rps18 (sepsis 1 477 [528–4 721] vs controls 48 [0–220], p < 0.0001), but not mt-CO3 (sepsis 447 [167–1 450] vs controls 324 [170–739], p=0.1145), were elevated in patients with acute sepsis compared to controls (Figures 2A–C).