FGF13 and diabetic kidney disease: Fibroblast growth factor 13 (FGF13) is a participator of the FGF homologous factors (FHFs) subfamily and is also an ancestral gene of the FGF family (Itoh and Ornitz, 2008; Sun et al., 2023) found that the expression of FGF13 was increased in GECs in DKD and the specific deletion of FGF13 in endothelial cell ameliorated the apoptpsis of HFD + STZ-induced glomerular cell, which suggest that the expression of FGF13 has a positive relation with T2DN.