PINK1 and diabetic kidney disease: Enhancing the level of intracellular mitophagy has a significant renoprotective effect in DKD and supplementation with MitoQ, a mitochondrial antioxidant, was confirmed to protect against DKD through upregulating the levels of mitophagy via Nrf2/PTEN-induced putative kinase protein 1 (PINK1) (Tagawa et al., 2016; Xiao et al., 2017; Yang et al., 2019b).