CASP3 and acute myocardial infarction: In a rat model of acute myocardial infarction, Atractylodesin III reduces apoptosis of cardiomyocytes in acute myocardial infarction by decreasing the expression of Bax and CASP3, and up-regulating the ratio of Bcl-2 and Bcl-2/Bax (Cao M. et al., 2019).