KRT5 and epidermolysis bullosa simplex: In our cohort of EBS patients, we identified two patients with KRT5 variants and three patients with KRT14 variants with various clinical expressions, from a mild phenotype with localized blisters affecting the acral areas, nail dystrophy, and dyspigmentation (case 3, Table 1), to intermediate forms (cases 2 & 4, Table 1) that displayed herpetiform blistering with erosions that were more widespread to severe forms (cases 1 and 5, Table 1), with important skin fragility with blisters and erosions on large areas of the skin.