STK38 and neoplasm: Another study demonstrated that the mechanism behind the accumulation of damaged mitochondria in Stk38 KO cells involves PINK1/PARKIN mediated mitophagy and NDR1 deficiency decreases the cell survival of the transformed cells after ECM detachment (Bettoun et al., 2016), hinting that a common maladaptive feature of NDR kinases is tumor metastasis.