MDH1 and neoplasm: STS with IDH‐wildtype GB may have developed different mechanisms for decreasing high levels of ROS including low levels of tumor FABP7 expression to decrease DHA uptake, the production of large amounts of proteins with antioxidant properties, such as RNH1, and the metabolic reprogramming of tumor cells or GASCs supported by high levels of MDH1 production (Fig. 5).