INS and diabetes mellitus: After adjusting for the covariates of age, sex, heart rate, diabetes, Killip class, location of culprit lesion and TIMI flow grade 0 or 1 pre-percutaneous coronary intervention (PCI), oral hypoglycemic drugs, insulin therapy, HbA1C%, CKMB mass, myoglobin, brain natriuretic peptide (BNP), high-sensitive C-reactive-protein (hsCRP), LVMASS, infarct size, and extent of MVO, fasting SHR was found to be an independent determinant of impaired LVEF, LVGFI, GRS, and GLS (Table 3), with β = − 6.815, − 5.403, − 1.330, and 1.375, respectively.