Notably, human bone marrow-derived MSCs (hMSCs) exposed to in vitro culture conditions and bronchoalveolar lavage fluid (BALF)samples obtained from ARDS patients exhibited differential expression of genes encoding known MSC-secreted mediators, including angiopoietin 1, fibroblast growth factor 7 (FGF-7), and IL-6 [14]. The gene discussed is IL6; the disease is acute respiratory distress syndrome.