Mutations in CRB1 often lead to a wide spectrum of retinal dystrophies, such as retinitis pigmentosa type 12 (RP12), Leber congenital amaurosis type 8 (LCA8), pigmented paravenous chorioretinal atrophy, and retinitis pigmentosa with coat’s-like exudative vasculopathy [11–14]. This evidence concerns the gene CRB1 and Retinal dystrophy.