Conversely, exposure to miRNA-34a/Tat-A86 at a concentration equivalent to that of miRNA-34a (10 μM) resulted in significant inhibition of tumor spheroid growth, manifested by alterations in shape from day 6 onward (Fig. 8c, d), with a noteworthy decrease in spheroid size on day 10 post-treatment. Here, TAT is linked to neoplasm.