Zhang et al. presented new evidence indicating that the expression of lncRNA CCAT1 was also significantly elevated in the tissues and plasma exosomes of patients with GC; moreover, lncRNA CCAT1 was confirmed to interact directly with polypyrimidine tract binding protein 1 (PTBP1) and effectively maintain its stability by inhibiting the ubiquitin-mediated degradation process, thus to facilitate the transition from PKM1 to PKM2 to augment glycolysis in GC cells [150]. Here, PKM is linked to gastric cancer.