Meanwhile, hypoxic tumour cell-derived exosomal miR-340-5p and angiopoietin-like 4 (ANGPTL4) were evidenced to confer radioresistance in ESCC and NSCLC by targeting KLF10/UV radiation resistance-associated gene (UVRAG) and inhibiting ferroptosis, respectively [371, 372]. This evidence concerns the gene ANGPTL4 and neoplasm.