They trigger the formation of NETs, leading to the production of cytokines including CSF-IL-8/CSF-CXCL-8, CSF-IL-6, CSF-IL-1β, CSF-TNF-α, and mediate the recruitment of other immune cells to regulate acute and chronic inflammation processes that can lead to ARDS. This evidence concerns the gene CXCL8 and acute respiratory distress syndrome.