In terms of laboratory indicators, the statistical description of CSF-MPO, CSF-IL-6, CSF-IL-8, CSF-IL-18, CSF-IL-1β, and CSF-TNF-α in the poor prognosis group of bacterial meningitis were: 21.68 ± 5.48, 170.46 ± 54.25, 6743.81 ± 2078.98, 52.95 ± 17.07, 5.82 ± 1.91, 47.44 ± 13.80, respectively. The gene discussed is CXCL8; the disease is bacterial meningitis.