IFITM2 and colorectal carcinoma: Multivariate regression analysis of these factors showed that N stage (HR = 1.486, p = 0.025), M stage (HR = 3.153, p < 0.001), pathologic stage (HR = 2.450, p = 0.019), and IFITM2 expression level (HR = 2.620, p < 0.001) were significant risk factors affecting survival in patients with CRC (Table 3 and Fig. 3).