Others included 41 GWS genes for GERD (Pgene-GERD < 2.62 × 10−6, Supplementary Data 8), 11 for PUD (Pgene-PUD < 2.62 × 10−6, Supplementary Data 9), three (RNF5, HLA-DQA1, and HLA-DQB1) for gastritis-duodenitis (Pgene-gastritis-duodenitis < 2.62 × 10−6, Supplementary Data 10), and three (HLA-C, PITPNM2, and MPHOSPH9) for IBS (Pgene-IBS < 2.62 × 10−6, Supplementary Data 11). Here, RNF5 is linked to irritable bowel syndrome.