Other MHC-related pathways, including ‘MHC class II receptor activity’ (T2D–diverticular disease, T2D–IBD, and T2D–IBS), ‘MHC protein complex’ and ‘MHC protein complex assembly’ (T2D–GERD, T2D–diverticular disease, T2D–IBD, and T2D–IBS), were also significantly enriched. This evidence concerns the gene HLA-C and irritable bowel syndrome.