As shown in Fig. 10, levels of D1R and D2R protein expression in the striatum of were significantly higher in the control group than in the PD group (1.02 ± 0.04 vs 0.47 ± 0.08, P < 0.05, F = 13.498; 1.02 ± 0.04 vs 0.53 ± 0.15, P < 0.001, F = 40.017). This evidence concerns the gene DRD1 and Parkinson disease.