We could identify two groups of analytes with differential associations: (i) HGF, SDF-1α, IL-2R, CD30, TNF-RII, IL-16, MIF, APRIL, and SCF were negatively associated with sCeAD, CRP, lipids, platelets, and female sex, and positively associated with AIS, LAA, CE, SVO, age, diabetes, dyslipidaemia, hypertension, HbA1c, atrial fibrillation, and a positive history of a transient ischaemic attack. The gene discussed is TNFRSF8; the disease is hypertensive disorder.