PRF1 and inflammatory bowel disease: A total of five SWDEGs (CXCL9, GIMAP2, ADAMTS5, GRAP, and PRF1) were screened from the intersection of SDEGs, IBD positively correlated gene modules (‘MEblack’, ‘MEyellow’, and ‘MEblue’) and NASH positively related gene module (‘MEbrown’) (Fig. 5E).