SLC2A3 and gestational diabetes: In this study, we used STZ to construct a GDM mice model and found that compared with normal pregnant mice, the expression level of GLUT3 on the trophoblast membrane and the activity of AMPK in the trophoblast of GDM mice were significantly down-regulated.In vivo experiments have confirmed that AICAR can activate AMPK, thereby improving the abnormal localization of mice trophoblasts GLUT3 and increasing the glucose uptake of mice trophoblasts.