However, a few studies focused on the relationship between AMPK and GLUT3 have found that AMPK in the activation of colon cancer cells can promote GLUT3 expression, and the level of GLUT3 is significantly up-regulated in the use of the AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR)31. Here, SLC2A3 is linked to malignant colon neoplasm.