As noticed, among the assessed parameters, contrarywise to biochemical ones apart from ALT (p = 0.045, OR: 1.03, 95% CI: 1.001-1.061) (insulin: p = 0.766, glucose: p = 0.85, HOMA-IR: p = 0.918, AST: p = 0.77, total cholesterol: p = 0.6, TG: p = 0.474, HDL: p = 0.665, LDL: p = 0.626), a significant association between various body composition indexes and HCC overall occurrence was highlighted. This evidence concerns the gene INS and hepatocellular carcinoma.