The 8 cell types were annotated based on the differentially expressed markers: Bnip3 for autophagic cancer cells, Mki67 for proliferating cancer cells, Cd14, Apoe, C1qc, Mrc1, Lyz2 for monocytes, Col3a1 for fibroblasts, Cd3e and Gzma for T cells, Flt1 for endothelial cells, and Klk1 for DCs (Fig. 6C and Supplementary Fig. S6B, C). This evidence concerns the gene C1QC and cancer.