Low and high doses of O3FA ameliorated BPF-induced hypothyroidism-mediatedreduction in sperm quality, testosterone, luteinizing hormone,follicle-stimulating hormone, catalase, superoxide dismutase, totalantioxidant capacity, and nuclear factor erythroid 2-related factor 2 andincreases in estrogen, malondialdehyde, c-reactive protein, interleukin 1beta, caspase 3. This evidence concerns the gene IL1B and hypothyroidism.