In the models including only maternal predictors, TNF-α at the 1st GDM visit was inversely associated with offspring weight [β-coefficient= -0.090 (CI: -0.170; -0.010), p=0.028] and BMI [β-coefficient= -0.455 (CI: -0.773; -0.137), p=0.005], and positively with SGA [OR= 1.609 (CI: 1.036; 2.500), p=0.034]. The gene discussed is TNF; the disease is gestational diabetes.