In contrast, IL-10 down-regulated in feedback to infection of the A549 cell line with sensitive [P=0.002; P=0.004]; INHR [P=0.02; P=0.007]; RifR [p=0.2; P=0.01]; MDR [P=0.01; P=0.004]; XDR [p=0.1; P=0.004] Mtb strains 24 and 48 hr post-infection, respectively. The gene discussed is IL10; the disease is infection.