STXBP2 and microvillus inclusion disease: One such example is microvillus inclusion disease (MVID), a congenital enteropathy characterized by early-onset diarrhea, caused by mutations in myosin 5b (MYO5B), STX3 or syntaxin binding protein 2 (STXBP2) (Aldrian et al., 2021; Al-Yaqoubi, 2023).