PRPH2 mutations are associated with various retinal diseases (Stenson et al., 2020; Peeters et al., 2021), ranging from pattern dystrophy to macular dystrophy and retinitis pigmentosa [reviewed in Stenson et al. (2020) and Tebbe et al. (2020)]. The gene discussed is PRPH2; the disease is Abnormal retinal morphology.