CD40LG and infection: There were also modest but significant increases post-infection in both IgM and IgG specific for SARS-CoV-2 spike protein (p = 0.048 and p = 0.023 respectively), CMV (p = 0.006 and p = 0.007 respectively), EBV (p = 0.002 and p = 0.003 respectively), tetanus toxoid (p = 0.001 and p = 0.002 respectively), and RSV (p = 0.022 and p = 0.0035 respectively) (Figures 1A, B).