Similarly, when analyzing cytokine production upon PMA/Ionomycin stimulation, a steady increase in IFN-g+ CD4+ T cells from 1-4 weeks post-infection, and only a minor shift in IL-4+ CD4+ T cells around 2 weeks post-infection was detected (Figures 1E, F, Supplementary Figure 1B). The gene discussed is IL4; the disease is infection.