Likewise, IFN-γ has also been shown to promote inflammation in mouse models of and/or patients with psoriasis (31), alopecia areata (32), and hyperinflammatory diseases, such as primary hemophagocytic lymphohistiocytosis, and several forms of secondary hemophagocytic lymphohistiocytosis, such as macrophage activation syndrome (33). The gene discussed is IFNG; the disease is alopecia areata.