Finally, we further elucidated the correlation of transcriptional regulatory activities among different subpopulations of cardiomyopathic fibroblasts and found that C3 AGT + Fibroblasts in N were highly correlated with C0 THBS4+ Fibroblasts and C2 FGF7+ Fibroblasts that were also in N. C3 AGT + Fibroblasts in DCM and C3 AGT + Fibroblasts in RM were highly correlated. The gene discussed is THBS4; the disease is familial dilated cardiomyopathy.