sPD-L1 was detected with higher frequency in GC patients (90/117, 76.9%) than in NSCLC patients (6/72, 8.3%), whereas bsPD-L1 was detected with similar frequencies in GC patients (17/117, 14.5%) and NSCLC patients (17/72, 22.2%). The gene discussed is SPDL1; the disease is gastric cancer.