BRCA1 and cancer: A germline genetic analysis was performed by next-generation sequencing and deletion/duplication testing of 22 cancer predisposition genes (APC, ATM, BMPR1A, BRCA1, BRCA2, BRIP1, CDH1, CHEK2, EPCAM, MLH1, MSH2, MSH6, MUTYH, NBN, PALB2, PMS2, PTEN, RAD51C, RAD51D, SMAD4, STK11, and TP53) using an Invitae multigene panel.